Generally speaking, when making power changes in the cruise once leaned, do
you just adjust your throttle and/or RPM and THEN adjust mixture? I imagine
you wouldn't push mixture to full rich before making power changes at
altitude. Is this the case?

Further question: when going from, say, 24 inches and 2500 RPM leaned to 21
inches and 2500 RPM, would you generally need to adjust mixture at all?

Thanks in advance.