Joe, one of the trips I did several years ago ...

Day One:
From Portland, drive east up the Columbia River gorge to The Dalles.
Take you time and stop along the way at all the water falls, the dam,
fish hatchery, etc.
Day Two:
Go south on the two-lane to Bend. Have lunch, tour the town, go to the
Columbia factory (I didnt't get a chance to when I was there). Continue
south, do the lava tube tour (kids love it!). Next, stop a the cinder
cone and museum. Continue south to Crater Lake.
Day Three+:
Get up early, eat breakfast in the lodge. Drive around to the boat tour.
Get off at Wizard Island, eat your picnic lunch at the top of the cone.
Walk back down, catch the next boat, enjoy the tour around the rest of
the lake. Drive east around the crater. Have dinner at the lodge. Got to
the outdoor ranger program that night. Get a relaxing night's sleep.
Day Four:
Drive west, following the Rogue River. Stop and enjoy the pulloffs and
overlooks. Stop in Medford and take the Harry & David's tour. Go
northwest on I5 to US199. Take US199 southwest to Cresent City CA.
Day Five:
Leave early. Take US101 north along the coast. Stop and see the Redwood
Forest. Continue north to Gold Beach. Take the jet boat up the Rogue
River. The long trip takes you 50 miles upstream. When you get back have
dinner or continue driving north on US101 until you are ready to stop.
Day Six:
Continue north on US101. Stop where and when you like. There is much to
see. Continue north to North Lincoln (?). You now have a choice,
continue north on US101 or turn east onto Oregon 18. 101 will take you
to Tillamok, 18 will take you to McMinville and the Evergreen Museum.

Day Seven:
Of course, you could always go to Tillamok, then backtrack and go to
McMinville. If you went to Tillamok, you will spend the night there or
McMinville. After a good night's rest you will be ready to tour the
Evergreen Museum. Drive to Portland, enjoy a relaxing meal along the
Willamette River on the west bank.