The two main methods for homebuilt construction would be casting vs.
machining or some combination of both (probably the best option).
Forging probably isn't appropriate for home construction (either the
piston or connecting rod).

One method I have thought of is to produce a wax model of the engine
with molds (to a fairly high tolerance to minimize machining) which is
then cast using lost wax casting techniques. I planned to have an
integral cylinder head/cylinder/half the crank case (this is for an
opposed style engine). The only bolts would be to bolt the two halves
together.

A completely machined engine would need a large block of aluminium to
start with which I'm not sure how practical that would be. Perhaps
lost foam casting could be used as a general model of the engine was
made in foam and then cast and the resulting casting could be
machined.

Brock