For bug smasher planes cruising between 100-125kt, the sweet spot of
straight line travel distance is about 200 - 300nm. Assuming you have
someone picking you up at the destination, you can make a round trip in
a day while still have plenty of time spent at the destination, or make
the trip in two days and have a ton of time at the destination.

Most of the time the freeway distance is about 20% longer due to not
being a straight line. A 200-300nm distance will take a car 4-6 hours
of driving time, that makes a very tiring one day round trip. Even a
two day driving trip to a place 200-300nm away feels like driving a lot
on both days.