That works too. You can laser cut a template with the screw holes and center holes only and go the hole saw route. Only works for the round instruments. :-)

I tried it both ways and even with a drill press to hold the hole saw it wandered off center on me by about 0.05". I'm sure with practice I could get better but the hole saw was also slightly over size to the instruments and I literally needed to be on target to 0.002" because I had several instruments separated by the thickness of a sheet of paper or two.

CNC also works but takes more effort to get the tool offsets and cutter path programmed.

9B